2025년 6월 신약개발관련 주요 Deal
주요
라이센싱 및 파트너십
No |
Date |
Investors/ Licensee |
Service Provider/ Licensor |
Assets |
MoA |
Indication |
Stage |
Value (USD Mn) |
|
1 |
6/2 |
Benz Sciences |
Taiho Pharmaceutical |
SFG-03 |
LSD1 Inhibitor |
Oncology |
AML |
Preclinical |
n/d |
2 |
6/2 |
Regeneron |
Hansoh Pharma |
Olatorepatide (HS-20094) |
GLP-1R x GIPR dual agonist |
Metabolic disorder |
Obesity |
Phase 3 |
2,000 |
3 |
6/2 |
BMS |
BioNTech |
BNT327 |
αPD-1/L1xVEGF-A BsAb |
Oncology |
TNBC |
Phase 3 |
11,100 |
4 |
6/3 |
Eli Lilly |
Camurus |
FluidCrystal® |
Technology to develop long-acting incretin products |
Metabolic disorder |
Obesity, Diabetes |
- |
870 |
5 |
6/3 |
Alto Neuroscience |
Chase Therapeutics |
ALTO-207 |
Dopamine D3-preferring D3 / D2 agonist, 5-HT3 receptor antagonist |
Neurology |
Resistant depression |
Phase 2 |
71.5 |
6 |
6/3 |
Kiora Pharma |
Senju Pharma |
KIO-301 |
DHODH inhibitor |
Ophthalmology |
Inherited retinal diseases |
Phase 2 |
110 |
7 |
6/3 |
Transpire Bio |
Suzhou Intragrand Pharma |
Lenamilast (ITG-1052) |
PDE4 inhibitor |
Respiratory diseases |
Idiopathic pulmonary fibrosis |
Preclinical |
n/d |
8 |
6/4 |
Vividion Therapeutics (Bayer) |
Roche |
VVD-214 |
WRN inhibitor |
Oncology |
Solid tumors |
Phase 1 |
n/d |
9 |
6/4 |
Allarity Therapeutics |
Indiana Biosciences Research Institute |
Stenoparib |
PARP-1/2, TNKS1/2 inhibitor |
Oncology |
Advanced ovarian cancer, SCLC |
Phase 2 |
n/d |
10 |
6/4 |
Cullinan Therapeutics |
Genrix Bio |
Velinotamig |
αCD3xBCMA BsAb |
Immunology |
Autoimmune diseases |
Preclinical |
712 |
11 |
6/5 |
LigaChemBio |
NovaRock Biotherapeutics |
n/d |
ADC |
Oncology |
Solid tumors (Lung, Colorectal, Gastric, Pancreatic) |
n/d |
n/d |
12 |
6/5 |
n/d |
Ocugen |
OCU400 |
NR2E3-targeting gene therapy |
Ophthalmology |
Retinitis pigmentosa |
Phase 3 |
11 |
13 |
6/9 |
SOLVE FSHD |
Modalis Therapeutics |
MDL-1039433 |
DUX4-targeting gene therapy |
Neuromuscular diseases |
Facioscapulohumeral Muscular Dystrophy |
Preclinical |
n/d |
14 |
6/9 |
SK Plasma |
AimedBio |
n/d |
ROR1-targeting ADC |
Oncology |
Solid tumors |
Preclinical |
n/d |
15 |
6/9 |
BeOne Medicines |
Neowise Biotechnology |
n/d |
TCR-T cell therapies |
Oncology |
Solid tumors |
n/d |
n/d |
16 |
6/10 |
Acino |
AriBio |
AR1001 |
PDE-5 inhibitor |
Neurology |
Alzheimer’s disease |
Phase 3 |
600 |
17 |
6/10 |
Biohaven |
Bexorg |
BrainEx |
Whole-brain discovery platform AI engine |
Neurology |
- |
- |
n/d |
18 |
6/10 |
RayzeBio |
Philochem AG |
OncoACP3 |
ACP3-targeting RPT |
Oncology |
Prostate Cancer |
Preclinical |
1,350 |
19 |
6/11 |
Chiesi Farmaceutici |
Key2Brain |
n/d |
BBB-crossing ERTs |
Neurology |
Lysosomal storage disorders; |
Preclinical |
n/d |
20 |
6/11 |
Eli Lilly |
Juvena Therapeutics |
JuvNET |
AI enabled screening platform |
Musculoskeletal diseases |
Losing lean mass |
Preclinical |
650 |
21 |
6/11 |
Novo Nordisk |
Deep
Apple |
n/d |
Non-incretin GPCR targeting oral small molecule |
Cardio- metabolic disease |
Cardiometabolic diseases including obesity |
Preclinical |
812 |
22 |
6/11 |
Daewoong Pharmaceutical |
Salipro Biotech |
Salipro® |
Technology designed to stabilize membrane proteins |
- |
- |
- |
n/d |
23 |
6/13 |
AstraZeneca |
CSPC Pharmaceuticals |
YS2302018 |
Lp(a) disruptor |
Metabolic disorder |
Dyslipidemia |
Preclinical |
5,320 |
24 |
6/16 |
NextCure |
Simcere Zaiming Pharma |
SIM0505 |
CDH6-targeting ADC |
Oncology |
Solid tumors |
Phase 1 |
745 |
25 |
6/16 |
Pierre Fabre Laboratories |
Antares Therapeutics |
PFL-721
PFL-241 |
Mutant-specific EGFR exon 20 and HER2 exon 20 inhibitor Mutant-specific, brain penetrant, 4th generation EGFR inhibitor |
Oncology |
NSCLC
NSCLC |
Preclinical
Preclinical |
177 |
26 |
6/16 |
Shanghai Escugen Biotechnology |
SunRock Biopharma |
SRB123 |
CCR9-targeting ADC |
Oncology |
Solid tumors |
Preclinical |
n/d |
27 |
6/16 |
Fosun Pharma |
Teva |
TEV-56278 |
αPD1-IL2 ATTENUKINETM therapy |
Oncology |
Solid tumors; melanoma |
Phase 1 |
n/d |
28 |
6/17 |
Intact Therapeutics |
Processa Pharmaceuticals |
PCS12852 |
5-HT4 receptor agonist |
Gastrointestinal diseases |
Gastroparesis, Other gastrointestinal motility disorders. |
Phase 2 |
452.5 |
29 |
6/18 |
Oceanus Bio |
Avata Biosciences Holdings |
AVAT-021 AVAT-022 |
Cannabinoid receptors agonist Cannabinoid receptors agonist |
Neurology Neurology |
Schizophrenia Epilepsy |
Phase 1 Preclinical |
95 |
30 |
6/18 |
Synfini Inc. |
O2nix Bio |
n/d |
FTSJ1-targeting tRNA therapeutics |
Oncology |
Cancer |
Preclinical |
n/d |
31 |
6/23 |
Otsuka Pharmaceutical |
Harbour BioMed |
HBM7020 |
BCMAxCD3 bispecific T-cell engagers |
Immunology |
Autoimmune diseases |
Phase 1 |
670 |
32 |
6/23 |
Chuang Yi Global Asset Management |
Denovo Biopharma LLC |
Liafensine (DB104) |
SNDRI |
Neurology |
Treatment-Resistant Depression |
Phase 2 |
n/d |
33 |
6/23 |
Ono Pharmaceutical |
Vertex |
Povetacicept |
APRIL x BAFF dual antagonists |
Genitourinary diseases |
IgA nephropathy |
Phase 3 |
n/d |
34 |
6/23 |
Sanofi |
Libertas
Bio |
Gusacitinib |
JAK x SYK dual inhibitor |
Dermatology |
Dermatitis |
Phase 2 |
629.3 |
35 |
6/24 |
ABION Bio |
n/d |
ABN501 |
αCLDN mAb |
Oncology |
Solid tumors; Small cell lung cancer, Breast cancer, Ovarian cancer |
Preclinical |
1,300 |
36 |
6/25 |
Cyntec |
Rakuten Medical |
Alluminox™ |
IR700 dye-conjugated, light- activatable, target-specific photoimmunotherapy |
Oncology |
Head and neck cancer |
- |
n/d |
37 |
6/25 |
Gilead Sciences |
Kymera Therapeutics |
n/d |
CDK2 targeting molecular glue degrader |
Oncology |
Solid cancer; Breast cancer |
- |
750 |
38 |
6/26 |
Vor Bio |
RemeGen |
Telitacicept |
BAFF x APRIL dual inhibitor |
Immunology |
Autoimmune diseases; |
Marketed Marketed Phase 3 |
4,230 |
39 |
6/26 |
Calico Life
Sciences |
Mabwell Bioscience |
9MW3811 |
αIL-11 mAb |
Respiratory diseases Oncology |
Idiopathic Pulmonary Fibrosis
Advanced Malignant Solid Neoplasm |
Phase 1
Phase 1 |
596 |
40 |
6/26 |
Percheron Therapeutics |
Hummingbird Bioscience |
HMBD-002 |
αVISTA mAb |
Oncology |
Solid tumors |
Phase 1/2 |
n/d |
41 |
6/26 |
Novartis |
ProFound Therapeutics |
ProFoundryTM |
Protein detection platform |
Cardiovascular diseases |
n/d |
n/d |
750 |
42 |
6/30 |
Curadh MTR |
Alpha Fusion |
At-211 |
Astatine-211 based RPT |
Oncology |
n/d |
n/d |
n/d |
43 |
6/30 |
Summit Therapeutics |
Revolution Medicines |
Daraxonrasib Zoldonrasib Elironrasib (RMC-6291) |
Multi-selective RAS inhibitor
G12D-selective inhibitor
G12C-selective inhibitor
|
Oncology
Oncology
Oncology |
NSCLC, Pancreatic cancer
RAS mut. NSCLC
Unspecified cancer; colorectal cancer |
Phase 3
Phase 1/2
Preclinical |
n/d |
44 |
6/30 |
Shanghai Henlius Biotech |
FBD
Biologics |
HCB101 |
CD47/SIRPα inhibitor |
Oncology |
Solid tumors; Head and neck, Gastric, Colorectal and Breast cancers |
Phase 2 |
202 |
45 |
6/30 |
LG chem |
SPARK Biopharma |
PhenoCure+ |
pDOS Library Screening for PPI Inhibition |
n/d |
- |
- |
n/d |
46 |
6/30 |
Pfizer |
XtalPi |
XFEP/XFF |
AI-driven small molecular modeling platform |
n/d |
- |
- |
n/d |
(n/d=non-disclosure)
주요 M&A
No |
Date |
Acquires |
Issuer |
Assets |
MoA |
Indications |
Status |
Value (USD Mn) |
|
1 |
6/2 |
Sanofi |
Blueprint Medicines |
Ayvakit BLU-808 |
c-KIT, PDGFRA inhibitor
KIT D816V Wild type c-KIT |
Oncology Immunology Immunology Immunology |
GIST,
Indolent systemic mastocytosis Chronic urticaria |
Marketed
Phase2/3 Phase2 |
9,500 |
2 |
6/4 |
Continuity Biosciences |
Focal Medical |
Iontophoresis platform |
Drug delivery system |
Oncology |
Pancreatic cancer |
- |
n/d |
3 |
6/5 |
Juvenescence |
Ro5 |
AI drug Discovery platform |
DL-based affinity and pose prediction for target ID and compound prioritization |
Cardio-metabolic disease, etc. |
Cognition, cardio-metabolism, immunity, cellular repair |
- |
76 |
4 |
6/9 |
Concentra Biosciences |
Elevation Oncology |
EO-1022 |
HER3 targeting ADC |
Oncology |
Solid tumors |
Preclinical |
21.4 |
5 |
6/12 |
BioNTech |
CureVac |
CVGBM |
mRNA vaccine |
Oncology |
Glioblastoma |
Phase 1 |
1,250 |
6 |
6/16 |
Supernus Pharmaceutical |
Sage Therapeutics |
Zurzuvae |
GABA A receptor modulator |
Neurology |
Depression |
Marketed |
561 |
7 |
6/18 |
Eli Lilly |
Verve Therapeutics |
VERVE-102 |
Inactivating the PCSK9 gene in the liver |
Cardiovascular disease |
Atherosclerosis |
Phase 1 |
1,300 |
8 |
6/25 |
Launch One Acquisition Corp. |
Minovia Therapeutics Ltd. |
MNV-201 |
Hematopoietic stem cell therapy |
Metabolic disorder |
Mitochondrial
dysfunction; |
Phase 2 |
180 |
9 |
6/25 |
Novartis |
Regulus Therapeutics |
Farabursen |
miR-17 targeting ASO |
Genitourinary diseases |
Autosomal dominant polycystic kidney disease |
Phase 1 |
394.62 |
9 |
6/27 |
Xoma Royalty |
Turnstone Biologics |
n/d |
Selected tumor - infiltrating lymphocyte technologies |
Oncology |
Solid tumor |
n/d |
8 |
10 |
6/30 |
AbbVie |
Capstan Therapeutics |
CPTX2309 |
tLNP anti-CD19 CAR-T |
Immunology |
Autoimmune diseases |
Phase 1 |
2,100 |
11 |
6/30 |
Oncoinvent |
BerGenBio |
Radspherin |
224Ra α-RPT |
Oncology |
Peritoneal carcinomatosis |
Phase 1/2 |
43.3 |
Reference
각 사 홈페이지 / BioCentury / Globaldata / Cortellis
/ Fierce Biotech
이전
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