Season 2 (2021-2030)

Ophthalmology - Small Molecules (10)

Modality Indication Targets Stage Company Project No. Detail
1 Development of lead compound for Leber hereditary optic neuropathy
Small Molecules Leber hereditary optic neuropathy NQO1 Lead Curome Bioscience RS-2023-00259507
2 Investigational New Drug Application Profiling of CGK012, a PKCα activator, for treating age.related macular degeneration
Small Molecules Macular degeneration Protein kinase Cα / Wnt/β.catenin 신호전달 저해 Preclinical AREZ RS-2023-00259081
3 Non-clinical research for the development of dry macular degeneration
Small Molecules Dry AMD RIPK1 Preclinical Mother’s Pharmaceutical Co., Ltd RS-2023-00219642
4 Lead identification for retinal diseases using selective NO delivery compounds
Small Molecules Retinal vein occlusion Co, Fe Hit Ulsan National Institute of Science & Technology RS-2023-00217242
5 Discovery of first-in-Class AMD treatment for dry eye using Autophagy activation
Small Molecules Dry macular degeneration Autophage Lead VasThera RS-2022-00166507
6 Future Medicine FM101-Oral Glaucoma Treatment
Small Molecules Glaucoma, Ocular hypertension A3AR Phase 2 Future Medicine Co., Ltd. HN22C0520
7 Development of DWRX2008 as a Novel Therapeutic for Intractable Ocular Angiogenesis
Small Molecules Diabetic Retinopathy SGLT2 Preclinical Daewoong Therapeutics HN22C0450
8 To develop the lead of a new oral drug for age-related macular degeneration
Small Molecules Age-related macular degeneration PDK4 Hit Kyungpook National University HN21C0923
9 Nonclinical drug candidates targeting TRAP1 to treat diabetic retinopathy
Small Molecules Diabetic retinopathy TRAP1 Candidate SMARTIN BIO Inc. HN21C0882
10 Lead development of orally available drug for diabetic retinopathy targeting TGase 2 to inhibit vascular leakage
Small Molecules Diabetic retinopathy TGase2 Hit Daegu Gyyeongbuk Medical Innovation Foundation HN21C1155