| 1 |
Phase 2a (therapeutic exploratory) trial of SB17170 in patients with idiopathic pulmonary fibrosis |
| Small molecules |
IPF |
HMGB1 |
Phase 2 |
|
RS-2026-25502804 |
|
| 2 |
Development of a Pre-clinical Candidate for Progressive Fibrosing Interstitial Lung Disease Targeting gp130 (an IL-6 Family Cytokine) Inhibition |
| Small molecules |
Auto-immune Diseases & Progressive Fibrosing Interstitial Lung Disease |
gp130 |
Candidate |
Primo Thera CO., Ltd. |
RS-2025-25452684 |
|
| 3 |
Development of Selective PDE-4B Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis (IPF) |
| Small molecules |
Idiopathic pulmonary fibrosis |
PDE-4B |
Candidate |
Jeil Pharmaceutical |
RS-2025-02213196 |
|
| 4 |
Discovery of a novel small-molecule drug candidate targeting IL-33 |
| Small molecules |
Asthma |
IL-33 |
Candidate |
Azcuris Co., Ltd. |
RS-2024-00333140 |
|
| 5 |
Discovery of a ‘First.In.Class’ New Drug for IPF Treatment |
| Small molecules |
Idiopathic pulmonary fibrosis |
ARPC2 |
Candidate |
SapiensBio.Inc |
RS-2023-00283815 |
|
| 6 |
Phase I clinical study of SB17170 for the drug development for idiopathic pulmonary fibrosis |
| Small molecules |
Idiopathic pulmonary fibrosis |
HMGB1 |
Phase 1 |
SPARK Biopharma |
RS-2023-00259223 |
|
| 7 |
Development of Novel Agents for Idiopathic Pulmonary Fibrosis: Phase 2a Clinical Trial and phase 2b approval of BBT-877, autotaxin inhibitor, in IPF patients |
| Small molecules |
Idiopathic pulmonary fibrosis |
Autotacxin |
Phase 2 |
Bridge Biotherapeutics, Inc. |
RS-2023-00219938 |
|
| 8 |
Clinical Trial Development of A Novel Small Molecule Inhibitor for Idiopathic Pulmonary Fibrosis Treatment |
| Small molecules |
IPF |
Prolyl-tRNA synthetase (PRS) |
Phase 2 |
Daewoong Pharmaceutical Co., Ltd. |
RS-2022-00166689 |
|
| 9 |
ATB-610: Small molecule developing as a inhaler with reducing toxicity by inhibiting ALK5 selectively for IPF treatment |
| Small molecules |
IPF |
ALK5 |
Candidate |
Autotelic Bio |
RS-2022-00165740 |
|
| 10 |
Development of drug candidate against respiratory infection using Foxj1 as a target |
| Small molecules |
Pneumonia |
Foxj1 |
Lead |
Chonnam National University |
HN21C0513 |
|
| 11 |
Elicitation of lead compounds for the treatment of chronic obstructive pulmonary disease targeting leucotriene B4 receptor BLT2 |
| Small molecules |
COPD |
BLT2 |
Lead |
Korea university |
HN21C0996 |
|
| 12 |
Study on lead generation for IPF (idiopathic pulmonary fibrosis) drug based on AI platform |
| Small molecules |
IPF |
CHIT1 |
Lead |
INNOVO Therapeutics |
HN21C0205 |
|
| 13 |
Development of small-molecule asthma drug that inhibits the binding of IL-33 to its receptor |
| Small molecules |
Asthma |
IL-33 |
Lead |
AZCURIS |
HN21C0187 |
|