| 1 |
Development of a first-in-class therapeutic antibody lead targeting GTC-D1 for pulmonary fibrosis |
| Antibody |
IPF |
GTC-D1 |
Hit |
Good T cells, Inc. |
RS-2025-25455100 |
|
| 2 |
ASO-Based Therapeutics Targeting ATX for Pulmonary Fibrosis |
| Gene & Nucleic acids |
Pulmonary fibrosis |
ATX (autotaxin) |
Hit |
Sookmyung Women's University |
RS-2025-02213647 |
|
| 3 |
Development of antibodies to induce lung regeneration for the treatment of emphysema |
| Antibody |
Pulmonary emphysema |
Robo1 |
Hit |
Asan Medical Center |
HN21C0202 |
|
| 4 |
Development of therapeutic fully human monoclonal antibody FBPF-11X as lead compound for pulmonary fibrosis |
| Antibody |
Pulmonary fibrosis |
FBFP-101-T |
Lead |
FNCT Biotech |
HN22C0683 |
|
| 5 |
|
| Other-Bio. |
Bronchopulmonary Dysplasia(BPD) |
Ago2 |
Lead |
Samsung Medical Center |
HN22C0414 |
|
| 6 |
Derivation of lead candidates for idiopathic
pulmonary fibrosis treatment through inhalant
optimization of integrin selective binding peptide |
| rProtein |
IPF |
Integrin αVβ-3,5,6 |
Lead |
NEXEL |
HN22C0012 |
|
| 7 |
Development of drug candidate against respiratory infection using Foxj1 as a target |
| Small molecules |
Pneumonia |
Foxj1 |
Lead |
Chonnam National University |
HN21C0513 |
|
| 8 |
Elicitation of lead compounds for the treatment of chronic obstructive pulmonary disease targeting leucotriene B4 receptor BLT2 |
| Small molecules |
COPD |
BLT2 |
Lead |
Korea university |
HN21C0996 |
|
| 9 |
Study on lead generation for IPF (idiopathic pulmonary fibrosis) drug based on AI platform |
| Small molecules |
IPF |
CHIT1 |
Lead |
INNOVO Therapeutics |
HN21C0205 |
|
| 10 |
Development of small-molecule asthma drug that inhibits the binding of IL-33 to its receptor |
| Small molecules |
Asthma |
IL-33 |
Lead |
AZCURIS |
HN21C0187 |
|
| 11 |
Development of a Pre-clinical Candidate for Progressive Fibrosing Interstitial Lung Disease Targeting gp130 (an IL-6 Family Cytokine) Inhibition |
| Small molecules |
Auto-immune Diseases & Progressive Fibrosing Interstitial Lung Disease |
gp130 |
Candidate |
Primo Thera CO., Ltd. |
RS-2025-25452684 |
|
| 12 |
Development of a Lung-Selective RNA Therapeutic Candidate for lung fibrosis |
| Gene & Nucleic acids |
IPF |
**** |
Candidate |
Samyang Biopharm |
RS-2025-25448962 |
|
| 13 |
Development of Selective PDE-4B Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis (IPF) |
| Small molecules |
Idiopathic pulmonary fibrosis |
PDE-4B |
Candidate |
Jeil Pharmaceutical |
RS-2025-02213196 |
|
| 14 |
Development of CSF3 targeted Pre-clinical Candidate Human Monoclonal Antibody FB-101 for Pulmonary Fibrosis |
| Antibody |
Idiopathic Pulmonary Fibrosis |
CSF3 |
Candidate |
FNCT Biotech, Inc. |
RS-2024-00461975 |
|
| 15 |
Discovery of a novel small-molecule drug candidate targeting IL-33 |
| Small molecules |
Asthma |
IL-33 |
Candidate |
Azcuris Co., Ltd. |
RS-2024-00333140 |
|
| 16 |
Discovery of a ‘First.In.Class’ New Drug for IPF Treatment |
| Small molecules |
Idiopathic pulmonary fibrosis |
ARPC2 |
Candidate |
SapiensBio.Inc |
RS-2023-00283815 |
|
| 17 |
ATB-610: Small molecule developing as a inhaler with reducing toxicity by inhibiting ALK5 selectively for IPF treatment |
| Small molecules |
IPF |
ALK5 |
Candidate |
Autotelic Bio |
RS-2022-00165740 |
|