1 |
Discovery of a ‘First.In.Class’ New Drug for IPF Treatment |
Small Molecules |
Idiopathic pulmonary fibrosis |
ARPC2 |
Candidate |
SapiensBio.Inc |
RS-2023-00283815 |
|
2 |
Phase I clinical study of SB17170 for the drug development for idiopathic pulmonary fibrosis |
Small Molecules |
Idiopathic pulmonary fibrosis |
HMGB1 |
Phase 1 |
SPARK Biopharma |
RS-2023-00259223 |
|
3 |
Development of Novel Agents for Idiopathic Pulmonary Fibrosis: Phase 2a Clinical Trial and phase 2b approval of BBT-877, autotaxin inhibitor, in IPF patients |
Small Molecules |
Idiopathic pulmonary fibrosis |
Autotacxin |
Phase 2 |
Bridge Biotherapeutics, Inc. |
RS-2023-00219938 |
|
4 |
Clinical Trial Development of A Novel Small Molecule Inhibitor for Idiopathic Pulmonary Fibrosis Treatment |
Small Molecules |
IPF |
Prolyl-tRNA synthetase (PRS) |
Phase 2 |
Daewoong Pharmaceutical Co., Ltd. |
RS-2022-00166689 |
|
5 |
ATB-610: Small molecule developing as a inhaler with reducing toxicity by inhibiting ALK5 selectively for IPF treatment |
Small Molecules |
IPF |
ALK5 |
Candidate |
Autotelic Bio |
RS-2022-00165740 |
|
6 |
Development of drug candidate against respiratory infection using Foxj1 as a target |
Small Molecules |
Pneumonia |
Foxj1 |
Lead |
Chonnam National University |
HN21C0513 |
|
7 |
Development of antibodies to induce lung regeneration for the treatment of emphysema |
Small Molecules |
Pulmonary emphysema |
Robo1 |
Hit |
Asan Medical Center |
HN21C0202 |
|
8 |
Elicitation of lead compounds for the treatment of chronic obstructive pulmonary disease targeting leucotriene B4 receptor BLT2 |
Small Molecules |
COPD |
BLT2 |
Lead |
Korea university |
HN21C0996 |
|
9 |
Study on lead generation for IPF (idiopathic pulmonary fibrosis) drug based on AI platform |
Small Molecules |
IPF |
CHIT1 |
Lead |
INNOVO Therapeutics |
HN21C0205 |
|